What is Arthred® hydroysed collagen?

Arthred® hydrolysed collagen peptides is produced by enzymatic hydrolysis of collagen from the hides of German cattle under controlled conditions. Arthred® contains a highly bioavailable form of collagen. Clinical studies show 95% absorption. It is the tiny molecular size which is key to this absorption. The collagen in Totally Derma® Skin Beverage is 3 kdaltons, compared with around 70 kdaltons for most collagen supppliments.

Because it is sourced from animal collagen, the amino-acid composition of the peptides resembles that of human collagen. This is different to collagen from marine and whey sources which have a different chemical structure.

How do the active ingredients in Totally Derma® address the ageing process?

The collagen included in the formulation of Totally Derma® has been enzymatically hydrolysed, or pre-digested, to ensure fast absorption in the small intestine within an hour, before entering the blood vessels, thereby facilitating its optimum body utilisation. Studies of radio-labelled high-quality bovine collagen peptides show that, once absorbed, collagen peptides are distributed throughout all areas of the body – not only in the joints but also in the skin, demonstrating that high-quality collagen can be efficiently absorbed where needed, and that it is not wasted or lost through urine. Collagen and HA work together to stimulate each other’s production through a positive feedback mechanism: the more collagen that is present, the more HA is produced, and HA itself stimulates fibroblast cell growth within the collagen matrix of the dermis, which in turn will promote further collagen production.

Studies show older skin dramatically loses its ability to produce Hyaluronic acid thus resulting in skin with a loss of volume and formation of wrinkles and folds. Ingested Hyaluronic acid helps to restore the skin’s volume and promote a smooth, plump, natural appearance to the skin, thus filling wrinkles from the inside. Synergistic co-factors including Vitamin C, grape seed extract, green tea extract and alpha lipoic acid are also added to enhance and promote stages of collagen synthesis, maintenance, promotion and repair.

How does Totally Derma® differ from collagen drinks?

Totally Derma® contains 200% and 40% more collagen than other supplements (*in the form of 10,000 mg. of therapeutic dosage Arthred hydrolysed animal sourced collagen).

Totally Derma® contains a therapeutic dosage of 210 mg. Hyaluronic Acid which is up to 300% more than other supplement.

Totally Derma® contains synergistic dosages of Grape Seed Extract, Green Tea Extract, Alpha Lipoic Acid, Vitamin C, Zinc, Manganese, Copper – some other skin drinks contain Vitamin C and other co-factors.

Why is Arthred® Hydrolysed Collagen different?

Arthred® differs from other hydrolysed collagens as it contains a more complete spectrum of Collagen Type I, II and III.

It also differs by being processed through a proteolytic enzymatic hydrolysis process under controlled conditions. This means the proteolytic enzymes facilitate the cleavage of the amino acid peptide bonds. Whereas most other hydrolysed collagens on the market are just hydrolysed through a water process alone. The benefits of an enzymatic hydrolysis are smaller short chain amino acid peptides which are uniform and consistent in size thereby guaranteeing a 95% absorption rate.

Most collagen producers do not hydrolyse with proteolytic enzymes as the process takes much longer than standard hydrolysis (up to 6 hours per batch), this makes the process expensive and time–‐consuming, but it definitely yields the most superior form of hydrolysed collagen.

What is hyaluronic acid?

Hyaluronic Acid is a major component of the dermis and its fluidity. Hyaluronic Acid hydrates the skin and increases its volume and density whilst also supporting collagen and elastin within the skin. Hyaluronic acid is also involved in the rejuvenation of joint tissue and immune function and supports the biochemical processes involved in wound healing.

Totally Derma® supplies an optimal 210 mg. (per serving) of patented Hyaluronic Acid powder which uses a proprietary enzymatic process to enhance absorption through the digestive tract to 95%. No other collagen drink supplement supplies this therapeutic dosage. Totally Derma contains up to 300% more HA than any other collagen drink supplement.

What is the full listing of ingredients, benefits and dosages?

10,000 mg. Arthred® Collagen Formula Arthred® hydrolysed collagen is enzymatically processed, resulting in its UNIFORM, pharma grade, low molecular size (3 kDa) which allows for a scientifically proven 95% absorption rate,
210 mg. Synovoderma HA SynovoDerma HA is prepared using a proprietary enzymatic process to reduce the molecular weight to between 50kDa – 200kDa Daltons.
CO-FACTORS Synergistic cofactors are also added to enhance and promote stages of collagen synthesis, repair, maintenance and prevention.
250 mg. Vitamin C is an essential component in the body’s production of collagen as it stimulates fibroblasts and converts proline to hydroxyproline. Vitamin C is scientifically shown to help maintain firm and youthful skin by combating collagen degradation and oxidative stress (it helps to repair aging and photo-damaged skin)
160 mg. Grape Seed Extract is a very powerful antioxidant. It bonds to collagen and negates free radicals, boosts collagen development and helps in the renewal of skin cells. Grape Seed extract helps skin stay firm, supple and moisturized. Procyanidins found in Grape Seed Extract are also shown to protect and repair the skin from sun damage.
160 mg. Green Tea Extract is naturally rich in antioxidants and is associated with multiple skin benefits. It protects skin from the damaging effects of free radicals and stimulates the skins microcirculation. It is a good anti-inflammatory for skin and most importantly inhibits collagenase (a natural enzyme that breaks down collagen). Numerous clinical studies show Green Tea Extract increases skin firmness, water content and elasticity.
60 mg. Alpha Lipoic Acid is one of the MOST powerful antioxidants. Studies show it can slow down the aging process of the body in general. Within the skin it reverses skin cell damage and is shown to improve fine lines and wrinkles. Alpha Lipoic Acid regenerates Vit C, Vit E and inhibits cross-linking which contributes to the formation of wrinkles.
5 mg. Zinc is an essential mineral for maintaining healthy, youthful skin. Zinc is well known for its properties in repairing UV damage in the skin and slowing down collagen degradation. Zinc is crucial for superoxide dismutase syntheses (protects against oxidative stress). Studies show it boosts Collagen synthesis and therefore helps to delay the formation of wrinkles.
3 mg. Manganese is also another essential mineral needed to build collagen and repair oxidative stress within the skin and body. Manganese strengthens immature collagen and influences its fibril size. The antioxidant effects of manganese have been shown to help prevent wrinkle formation and sagging skin.

Why does Totally Derma® contain hyaluronic acid?

Other Collagen Drink supplements which do not contain Hyaluronic Acid are missing out! Hyaluronic Acid also stimulates fibroblast proliferation within the collagen matrix. Therefore, Hyaluronic Acid stimulates collagen growth as well as directly consuming hydrolysed collagen. Therefore, drink supplements not containing HA can only do half the job that Totally Derma does regarding stimulating collagen.

Does Totally Derma® contain antioxidants? Which ones?

Totally Derma contains the following as antioxidants: Vitamin C, Zinc, Grape Seed Extract, Green Tea Extract, Alpha Lipoic Acid
Some collagen drinks contain B Vitamins. B Vitamins are not classed as antioxidants. The only antioxidant which many collagen supplements contain is Vitamin C.

How to use

Does the powdered formula affect its absorbability?

Totally Derma® does not need to be dissolved in a solution to be absorbed, it can be taken as a powder on its own or for taste reasons, mixed into a drink. Neither form of consumption affects its absorbability. It is still over 95% absorbed, no matter how it is taken. A single dose of Totally Derma® contains the equivalent of 26 capsule alternatives.

When is the best time to take Totally Derma®?

Drink it before bed as this is the best time to boost collagen levels. The majority of collagen synthesis takes place in your first couple of hours of sleep so it’s best to combine that with Totally Derma®. If that doesn’t suit your routine, drink it on an empty stomach or after food. Don’t drink a coffee within 2 hours of ingesting Totally Derma® as coffee is a diuretic.

Can Totally Derma® be mixed with other drinks?

It can be mixed with water, juice, milk, or even mixed into food such as yoghurt. It is great when added to your daily smoothie. Make sure you do not heat it – it is not to be mixed in hot drinks or food.

Can I take Totally Derma® in the day?

Yes, you can take Totally Derma® any time, but to ensure best absorption, please do not drink it within 90 minutes of having a coffee. Coffee is a diuretic, and you might be excreting it within 45 minutes.
Keep your coffee and TD separate by 2 hours.

Can I put Totally Derma® in my coffee or soup?

DO NOT HEAT Totally Derma®. It is a pre-digested powder, already in 95% absorption form, if you heat it, the amino acid peptides will be compromised, the molecular structure will be denatured.

Will the L-Ascorbic Acid Vitamin C irritate my stomach?

Ascorbic acid can irritate the stomach but only at doses from 1000mg upwards, certainly not 250mg which is the dosage in Totally Derma. (It is only mildly acidic) L-Ascorbic Acid is deliberately in the formula as it is the most effective/scientifically proven form of vitamin C for skin. It also contains superior antioxidant actions in the body due to having 2 antioxidant electrons rather than 1 electron as with calcium ascorbate.
Thus, calcium ascorbate is generally only half as effective as ascorbic acid. There are no studies to support mineral ascorbates in skin health.


Does Totally Derma® have any other benefits other than improving the skin on my face and body?

Yes! As Totally Derma® is an ingested product that circulates in the blood stream the ingredients are supplied to ALL the skin in your body – not just the face. It is proven to stimulate and replace other collagens in the body such as cartilage in joints. People often notice their aches and pains improve in their joints and spine after a few weeks. It is also beneficial for hair, nails, bone density and general dryness of mucous membranes. Therefore, it is a good all-round product for menopausal women especially.

Will Totally Derma® help my leaky gut?

Collagen is a mediator in the gut-skin relationship.

Collagen is a protein that is packed with the types of amino acids that our GI tract uses to repair and heal itself. By mending the damaged cells which comprise the gut lining, these amino acids regulate the gut microbiome and its permeability, thereby treating and preventing leaky gut syndrome.

How can Totally Derma® improve my joint health?

Inside the body, increased collagen and hyaluronic acid production means that stiff joints will become more flexible and comfortable, making this a great supplement for general health and fitness minded men and women. Totally Derma® has its medical heritage in repairing cartilage in joints, so is a fantastic supplement for anyone who has osteoarthritis.

Should I take this supplement for peri-post menopause?

Absolutely. Totally Derma® is beneficial for hair, nails, bone density and general dryness of mucous membranes. Therefore, it is a good all-round product for menopausal women especially. A small, self-reporting Totally Derma® study revealed promising results with the supplement offering relief for 90% of the participants across the full range of GSM (Genitourinary Syndrome of Menopause) symptoms.

I am having surgery shortly. Would Totally Derma® help?

Without a doubt. Many surgeons recommend Totally Derma® for their patients undergoing surgery (pre and post) as it is highly beneficial for wound recovery.

How long will it take to see results?

2-3 weeks for hydration.
6-12 weeks for wrinkle depth reduction, improvement in elasticity, density and plumpness.
12 weeks for improvement in joint health.


What is the difference between Totally Derma® and other collagen supplements?

1. Totally Derma® contains 30% more collagen, 300% more hyaluronic and 300% more antioxidants than its leading competitor. Totally Derma® contains the equivalent of 26 collagen capsule alternatives.
2. The amino acid content of a dose of Totally Derma contains higher level of ALL amino acids due to the fact Totally Derma contains 10,000mg. collagen in its 12,000mg per daily serving (the hyaluronic acid, 5 antioxidants and 2 minerals make up the rest of the formulation).
3. Totally Derma® contains a more complete spectrum of Collagens: Type I (hair, skin, nails, bones) Type II, (tendons, ligaments, cartilage) and Type III, (Intestinal walls and arteries) – Marine contains mainly type I collagen.
4. Bovine collagen biochemically resembles human collagen. The body recognises this collagen therefore utilises it a lot more effectively in the body.
5. Totally Derma® contains 210mg patented hyaluronic acid to further hydrate and lubricate skin, joints, eyes, vagina, etc.
6. Totally Derma® contains 250mg L-Ascorbic Vitamin C – (2 antioxidant electrons compared to mineral ascorbate).
7. Totally Derma® contains 5 therapeutic dosage antioxidants to reduce inflammation in the body and skin, and address cross-linking issues (wrinkles) in skin.
8. Totally Derma® has its own clinical studies for its formulation.

What is the difference between Marine Collagen and Bovine Collagen?

Bovine collagen biochemically resembles human collagen. The body recognises this collagen therefore utilises it a lot more effectively in the body.

Totally Derma® contains Arthred® – a patented type I, II, III spectrum collagen which contains the highest levels of the amino acids glycine, proline and alanine from any other collagen source.

Totally Derma® contains the highest levels of proline and hydroxyproline (these are the most important for collagen production) compared to Peptan fish derived collagen.